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BIOMARKERS IN ANIMAL MODELS - Syllabus
BIOMARKERS IN ANIMAL MODELS - Syllabus

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LUCIANO PINOTTI (responsabile dell'insegnamento)

CdL in SCIENZE BIOTECNOLOGICHE VETERINARIE (Classe LM-9) immatricolati 2014/2015 - Laurea Magistrale - 2015/2016

Insegnamento obbligatorio / Compulsory courseNo
Anno di corso / Year of course2s
Periodo di svolgimentosecondo / second trimestre
Settori scientifico disciplinari / Scientific fields
  • AGR/18 - Nutrizione e alimentazione animale (3 cfu: / ects: )
  • AGR/19 - Zootecnica speciale (2 cfu: / ects: )
  • VET/05 - Malattie infettive degli animali domestici (3 cfu: / ects: )
Crediti (CFU) obbligatori / ECTS credits (CFU) compulsory8
Crediti (CFU) facoltativi / ECTS credits - facultative-

Programma di studio / Syllabus

Programma / Syllabus Module: Biomarkers in animal nutrition:

AIM OF THE COURSE:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status o fan essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
Lectures
Nutritional (feed) behavior
Nutritional status evaluation
Vitamins status biomarkers
Antioxidant status biomarkers
Mineral status biomarkers


Tutorials/ractice training
Database use
Laboratory activities
Journal club

Programma / Syllabus Module: Biomarkers in animal nutrition per non frequentanti / not attendant students

AIM OF THE COURSE:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status o fan essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
Lectures
Nutritional (feed) behavior
Nutritional status evaluation
Vitamins status biomarkers
Antioxidant status biomarkers
Mineral status biomarkers


Other skills
database use
journal club

Bibliografia e altri materiali didattici / Readings Module: Biomarkers in animal nutrition:

Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Bibliografia e altri materiali didattici / Readings Module: Biomarkers in animal nutrition per non frequentanti / not attendant students

Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Programma / Syllabus Module: Diagnostic tools in animal infectious diseases:

Cultivation and identification of the main pathogens in animals
PCR and molecular methods
Serological methods: IFA, ELISA, HAE

Programma / Syllabus Module: Diagnostic tools in animal infectious diseases per non frequentanti / not attendant students

Cultivation and identification of the main pathogens in animals
PCR and molecular methods
Serological methods: IFA, ELISA, HAE

Bibliografia e altri materiali didattici / Readings Module: Diagnostic tools in animal infectious diseases:

Slides and papers

Bibliografia e altri materiali didattici / Readings Module: Diagnostic tools in animal infectious diseases per non frequentanti / not attendant students

Slides and papers

Programma / Syllabus Module: Laboratory techniques to test DNA-damage in animal models:

The main topic of the course concerns the introduction to fundamental bases of oxidative stress cell exposure and application of biomarkers based assays able to verify in vivo oxidative damage and anti-oxidant capacity. Mostly, the course examines the development of reactive intermediates which can covalently bind to DNA, resulting in bulky addition products called "adducts." DNA.
Lectures
Causes and occurrence of oxidative stress damage.
Evaluation of total anti-oxidant capacity and repairing mechanisms.
Application of biomarkers for the screening and monitoring of oxidative status.
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA.
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems.

Programma / Syllabus Module: Laboratory techniques to test DNA-damage in animal models per non frequentanti / not attendant students

The main topic of the course concerns the introduction to fundamental bases of oxidative stress cell exposure and application of biomarkers based assays able to verify in vivo oxidative damage and anti-oxidant capacity. Mostly, the course examines the development of reactive intermediates which can covalently bind to DNA, resulting in bulky addition products called "adducts." DNA.
Main topics:
Causes and occurrence of oxidative stress damage.
Evaluation of total anti-oxidant capacity and repairing mechanisms.
Application of biomarkers for the screening and monitoring of oxidative status.
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA.
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems.

Bibliografia e altri materiali didattici / Readings Module: Laboratory techniques to test DNA-damage in animal models:

Books
DNA adducts: formation, detection, and mutagenesis. Ed. Emerson Alvarez and Roberto Cunha. Publisher Nova Science Publishers Inc. 2010.
Davies, K.J.A. and Ursini, F., eds. (1996) The Oxygen Paradox, 811 pages, CLEUP University Press, Padova (Italy) ISBN: 8871783743; ISBN 13: 9788871783741.
Teacher's material (slides and papers) presented during lectures.

Bibliografia e altri materiali didattici / Readings Module: Laboratory techniques to test DNA-damage in animal models per non frequentanti / not attendant students

Books
DNA adducts: formation, detection, and mutagenesis. Ed. Emerson Alvarez and Roberto Cunha. Publisher Nova Science Publishers Inc. 2010.
Davies, K.J.A. and Ursini, F., eds. (1996) The Oxygen Paradox, 811 pages, CLEUP University Press, Padova (Italy) ISBN: 8871783743; ISBN 13: 9788871783741.
Teacher's material presented during lectures.

Modalità di esame, prerequisiti, esami propedeutici / Prerequisites, exams and assessment

Esame / Examunico
Modalità di accertamento conoscenze / Type of assessmentEsame
Giudiziovoto verbalizzato in trentesimi

Organizzazione didattica / Structure of the course

Module: Biomarkers in animal nutrition, Biomarkers in animal nutrition

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • AGR/18 - Nutrizione e alimentazione animale - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Module: Diagnostic tools in animal infectious diseases, Diagnostic tools in animal infectious diseases

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • VET/05 - Malattie infettive degli animali domestici - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Docenti / Teachers

Module: Laboratory techniques to test DNA-damage in animal models, Laboratory techniques to test DNA-damage in animal models

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • AGR/19 - Zootecnica speciale - cfu: / ects: 2
Attività didattiche previste / Learning activities

Lezioni: 12 ore / hours

Docenti / Teachers

Ricevimento docenti / Teacher's office hours

Orario di ricevimento Docenti / Teacher's office hours
Docente / TeacherOrario di ricevimento / Office's hoursLuogo di ricevimento / Office location
LUCIANO PINOTTI (responsabile dell'insegnamento)su appuntamentoSede di Via Trentacoste, 2
FEDERICA BELLAGAMBAvenerdì 14.00-16.00 e su appuntamentovia Trentacoste 2, 20134 Milano
PIERA ANNA MARTINO