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BIOMARKERS IN ANIMAL MODELS - Syllabus
BIOMARKERS IN ANIMAL MODELS - Syllabus

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LUCIANO PINOTTI (responsabile dell'insegnamento)

CdL in SCIENZE BIOTECNOLOGICHE VETERINARIE (Classe LM-9) immatricolati dal 2016/17 - Laurea Magistrale - 2017/2018

Insegnamento obbligatorio / Compulsory courseNo
Anno di corso / Year of course2s
Periodo di svolgimentosecondo / second trimestre
Settori scientifico disciplinari / Scientific fields
  • AGR/19 - Zootecnica speciale (2 cfu: / ects: )
  • VET/05 - Malattie infettive degli animali domestici (3 cfu: / ects: )
  • AGR/18 - Nutrizione e alimentazione animale (3 cfu: / ects: )
Crediti (CFU) obbligatori / ECTS credits (CFU) compulsory8
Crediti (CFU) facoltativi / ECTS credits - facultative-

Informazioni generali / general information

Obiettivi: The course addresses methods and techniques that are used in biomarkers defining and validation in different fields

Lingua dell'insegnamento / Language of instruction: english

Metodi didattici /Activities: lectures, lab activisties, visits, seminars.

Programma di studio / Syllabus

Pagina web di riferimento:

http://ariel.unimi.it/

Short description english flag

Biomarkers— nutritional, biochemical, functional, or clinical—are needed to support evidence-based decision, interpretation, and strategies related to animal nutrition and health. Accordingly, the course try to address the importance of biomarkers in different biological fields related to animal models and science.

Programma / Syllabus Module: Biomarkers in animal nutrition:

Aim of the course:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status of an essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
lectures (16h)

Nutritional behavior
Nutritional status evaluation
Micronutrient status biomarkers

Practice training (16h)
Laboratory activities
Journal club

Final examination
A seminar on a specific topic related to the course contents

Books
•Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Programma / Syllabus Module: Biomarkers in animal nutrition per non frequentanti / not attendant students

Aim of the course:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status of an essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
lectures (16h)

Nutritional behavior
Nutritional status evaluation
Micronutrient status biomarkers

Further knowledge
Methods in nutritional biomarkers evaluation
Principles of NMR


Final examination
A seminar on a specific topic related to the course contents

Books
• Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Bibliografia e altri materiali didattici / Readings Module: Biomarkers in animal nutrition:

http://ariel.unimi.it/

Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Bibliografia e altri materiali didattici / Readings Module: Biomarkers in animal nutrition per non frequentanti / not attendant students

http://ariel.unimi.it/

Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press

Programma / Syllabus Module: Diagnostic tools in animal infectious diseases:

Aim of these lessons is description of the main bacterial, fungal and viral infectious diseases and the tools for the identification of causative agents

Programma / Syllabus Module: Diagnostic tools in animal infectious diseases per non frequentanti / not attendant students

this course is only for frequenting students

Bibliografia e altri materiali didattici / Readings Module: Diagnostic tools in animal infectious diseases:

Slides

Bibliografia e altri materiali didattici / Readings Module: Diagnostic tools in animal infectious diseases per non frequentanti / not attendant students

this course is only for frequenting students

Programma / Syllabus Module: Laboratory techniques to test DNA-damage in animal models:

Lectures
Causes and occurrence of oxidative stress damage (3 hours).
Evaluation of total anti-oxidant capacity and repairing mechanisms (2 hours).
Application of biomarkers for the screening and monitoring of oxidative status (2 hours)
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA (3 hours).
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems (2 hours).

Programma / Syllabus Module: Laboratory techniques to test DNA-damage in animal models per non frequentanti / not attendant students

Lectures
Causes and occurrence of oxidative stress damage (3 hours).
Evaluation of total anti-oxidant capacity and repairing mechanisms (2 hours).
Application of biomarkers for the screening and monitoring of oxidative status (2 hours)
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA (3 hours).
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems (2 hours).

Bibliografia e altri materiali didattici / Readings Module: Laboratory techniques to test DNA-damage in animal models:

Materials and teacher 's presentation used during lectures are available in Ariel.
Books
DNA adducts: formation, detection, and mutagenesis. Ed. Emerson Alvarez and Roberto Cunha. Publisher Nova Science Publishers Inc. 2010.
Davies, K.J.A. and Ursini, F., eds. (1996) The Oxygen Paradox, 811 pages, CLEUP University Press, Padova (Italy) ISBN: 8871783743; ISBN 13: 9788871783741

Bibliografia e altri materiali didattici / Readings Module: Laboratory techniques to test DNA-damage in animal models per non frequentanti / not attendant students

Materials and teacher 's presentation used during lectures are available in Ariel.
Books
DNA adducts: formation, detection, and mutagenesis. Ed. Emerson Alvarez and Roberto Cunha. Publisher Nova Science Publishers Inc. 2010.
Davies, K.J.A. and Ursini, F., eds. (1996) The Oxygen Paradox, 811 pages, CLEUP University Press, Padova (Italy) ISBN: 8871783743; ISBN 13: 9788871783741

Modalità di esame, prerequisiti, esami propedeutici / Prerequisites, exams and assessment

Esame / Examunico
Modalità di accertamento conoscenze / Type of assessmentEsame
Giudiziovoto verbalizzato in trentesimi

Prerequisiti e modalità di esame Final examination will consist in a presentation that addresses the use of biomarkers in animal models.

The course will help the student in getting familiar with the main biomarkers that are relevant in animal science.

Final examination will consist in a presentation that addresses the use of biomarkers in animal models.

The course will help the student in getting familiar with the main biomarkers that are relevant in animal science.

Esami propedeutici consigliati / Propedeutical courses and exams (suggested) those suggested by the SBV couse

Organizzazione didattica / Structure of the course

Module: Biomarkers in animal nutrition, Biomarkers in animal nutrition

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • AGR/18 - Nutrizione e alimentazione animale - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Module: Diagnostic tools in animal infectious diseases, Diagnostic tools in animal infectious diseases

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • VET/05 - Malattie infettive degli animali domestici - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Module: Laboratory techniques to test DNA-damage in animal models, Laboratory techniques to test DNA-damage in animal models

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • AGR/19 - Zootecnica speciale - cfu: / ects: 2
Attività didattiche previste / Learning activities

Lezioni: 12 ore / hours

Ricevimento docenti / Teacher's office hours

Orario di ricevimento Docenti / Teacher's office hours
Docente / TeacherOrario di ricevimento / Office's hoursLuogo di ricevimento / Office location
LUCIANO PINOTTI (responsabile dell'insegnamento)su appuntamentoSede di Via Trentacoste, 2

Altre informazioni / Further information

The course addresses methods, tools and techniques that are used in animal science for health and nutritional evaluation