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MOLECULAR PATHOLOGY AND PARASITOLOGY - Syllabus
MOLECULAR PATHOLOGY AND PARASITOLOGY - Syllabus

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FABRIZIO CECILIANI (responsabile dell'insegnamento)

CdL in SCIENZE BIOTECNOLOGICHE VETERINARIE (Classe LM-9) immatricolati dal 2016/17 - Laurea Magistrale - 2017/2018

Insegnamento obbligatorio / Compulsory courseNo
Anno di corso / Year of course2s
Periodo di svolgimentosecondo / second trimestre
Settori scientifico disciplinari / Scientific fields
  • VET/03 - Patologia generale e anatomia patologica veterinaria (6 cfu: / ects: )
  • VET/06 - Parassitologia e malattie parassitarie degli animali (2 cfu: / ects: )
Crediti (CFU) obbligatori / ECTS credits (CFU) compulsory8
Crediti (CFU) facoltativi / ECTS credits - facultative-

Informazioni generali / general information

Obiettivi: Aim of the course is to provide students with instruments to understand the molecular bases of animal cancer, metabolic and parasitic diseases, and how they may be used as model for human counterparts
Students will learn how to link molecular modifications with diagnostics.

Lingua dell'insegnamento / Language of instruction: English

Metodi didattici /Activities: Lectures

Programma di studio / Syllabus

Short description english flag

The course is articulated in three teaching units: the Molecular Oncology unit is focused on the molecular basis of cancer. The pathogenesis of animal and human cancer process will be presented with an emphasis on molecular, genetic, cell biological and pathophysiological aspects of cancer and immunity.
The Pathophysiology coursework provides students with foundation in modern physiopathology, which will be analyzed from a molecular perspective. The major metabolic diseases in animals and humans will be described, the last ones with a specific focus on suitable animal models.
The animal models and parasitic diseases teaching unit will focus on selected parasitic diseases to present the contribution from available animal models to the molecular research and diagnostics, to the evaluation of the epidemiological risk linked to zoonotic infection, and to the development of effective vaccine programs and pharmacological treatments.

Programma / Syllabus Module: Animal models and parasitic diseases:

Lectures:
1. Genomic, immunologic and diagnostic techniques for the study of parasitic diseases in laboratory rodent species and dogs (4 hs)
2. Usefulness of animal models for the understanding of the genetic and pathogenetic basis of parasitic diseases (2 hs)
3. Evaluation of the epidemiological risk linked to parasitic zoonoses: contribution from the canine model (2 hs)
4. Comparative evaluation of vaccine program efficacy and antiparasitic treatments through clinical trials in canine model (2 hs).
Practices: unconventional animal models for the study of parasitic and vector-borne diseases (2 hs)

Programma / Syllabus Module: Animal models and parasitic diseases per non frequentanti / not attendant students

1. Genomic, immunologic and diagnostic techniques for the study of parasitic diseases in laboratory rodent species and dogs
2. Usefulness of animal models for the understanding of the genetic and pathogenetic basis of parasitic diseases
3. Evaluation of the epidemiological risk linked to parasitic zoonoses: contribution from the canine model
4. Comparative evaluation of vaccine program efficacy and antiparasitic treatments through clinical trials in canine model
5. Unconventional animal models for the study of parasitic and vector-borne diseases

Bibliografia e altri materiali didattici / Readings Module: Animal models and parasitic diseases:

Handouts will be uploaded on ARIEL platform

Bibliografia e altri materiali didattici / Readings Module: Animal models and parasitic diseases per non frequentanti / not attendant students

Handouts will be uploaded on ARIEL platform

Programma / Syllabus Module: Molecular Oncology:

Lectures
Molecular basis of oncogenesis - 1st part (2h)
Molecular basis of oncogenesis – 2nd part (2h)
Metastasis (2h)
Mechanisms of tumor escape (2h)
Cachexia (2h)
Infectious agents and cancer (2h)
The microbiota and cancer (2h)
Molecular biomarkers of tumors (4h)

Programma / Syllabus Module: Molecular Oncology per non frequentanti / not attendant students

Lectures:
Molecular basis of oncogenesis - 1st part (2h)
Molecular basis of oncogenesis – 2nd part (2h)
Metastasis (2h)
Mechanisms of tumor escape (2h)
Cachexia (2h)
Infectious agents and cancer (2h)
The microbiota and cancer (2h)
Molecular biomarkers of tumors (4h)

Bibliografia e altri materiali didattici / Readings Module: Molecular Oncology:

Handouts will be uploaded on ARIEL platform

Bibliografia e altri materiali didattici / Readings Module: Molecular Oncology per non frequentanti / not attendant students

Handouts will be uploaded on ARIEL platform

Programma / Syllabus Module: Pathophysiology:

LECTURES:
1. The Metabolic syndrome in domestic animals (Prof helga Sauerwein - Univesrity of Bonn - Erasmus exchange)
2. Diabetes
3. Obesity
4. Liver diseases
5. Hemathology

Programma / Syllabus Module: Pathophysiology per non frequentanti / not attendant students

LECTURES:
1. The Metabolic syndrome in domestic animals (Prof Helga Sauerwein - Univesrity of Bonn - Erasmus exchange)
2. Diabetes
3. Obesity
4. Liver diseases
5. Hemathology

Bibliografia e altri materiali didattici / Readings Module: Pathophysiology:

Handouts will be uploaded on ARIEL platform

Bibliografia e altri materiali didattici / Readings Module: Pathophysiology per non frequentanti / not attendant students

Handouts will be uploaded on ARIEL platform

Modalità di esame, prerequisiti, esami propedeutici / Prerequisites, exams and assessment

Esame / Examunico
Modalità di accertamento conoscenze / Type of assessmentEsame
Giudiziovoto verbalizzato in trentesimi

Prerequisiti e modalità di esame Written

Written

Esami propedeutici consigliati / Propedeutical courses and exams (suggested) none

Organizzazione didattica / Structure of the course

Module: Animal models and parasitic diseases, Animal models and parasitic diseases

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • VET/06 - Parassitologia e malattie parassitarie degli animali - cfu: / ects: 2
Attività didattiche previste / Learning activities

Lezioni: 12 ore / hours

Docenti / Teachers

Module: Molecular Oncology, Molecular Oncology

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • VET/03 - Patologia generale e anatomia patologica veterinaria - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Docenti / Teachers

Module: Pathophysiology, Pathophysiology

obbligatorio / compulsory

Settori e relativi crediti / Scientific fields

  • VET/03 - Patologia generale e anatomia patologica veterinaria - cfu: / ects: 3
Attività didattiche previste / Learning activities

Lezioni: 18 ore / hours

Ricevimento docenti / Teacher's office hours

Orario di ricevimento Docenti / Teacher's office hours
Docente / TeacherOrario di ricevimento / Office's hoursLuogo di ricevimento / Office location
FABRIZIO CECILIANI (responsabile dell'insegnamento)Dipartimento di Scienze Veterinarie e Sanità Pubblica - Sezione Patologia Generale e Parassitologia
CRISTINA LECCHIsempre, previo appuntamentoVia Celoria 10.
MICHELE MORTARINOMercoledì 11.00-12.00DIMEVET - Patologia Generale e Parassitologia